Center log ratio normalisation

Source: R/CLRnorm.R

Center log ratio normalisation

CLRnorm(sce, assayName = "counts", targetAssay = "data", offset = 1)

Arguments

sce

SCE object

assayName

Assay to normalise

targetAssay

Name of normalised assay

offset

Offset value added to raw counts

Value

SCE object

Examples

sce <- scuttle::mockSCE(ncells = 20, ngenes = 10)
sce <- CLRnorm(sce)
assay(sce, "data")[1:3, 1:3]